Improving patient care and the health of our community through research and education.

MMRF Logo for Website                                                            hcmc web logo

The Minneapolis Medical Research Foundation (MMRF) is a subsidiary of Hennepin Healthcare System, Inc., and operates as the research arm of Hennepin County Medical Center, an acute care research and teaching hospital in Minneapolis. MMRF is one of the largest nonprofit medical research organizations in Minnesota and consistently ranks in the top ten percent of all institutions receiving research funding from the National Institutes of Health.

Learn more about our research programs.

MMRF 2016 Year in Review

Researchers at the Minneapolis Medical Research Foundation (MMRF) were busy advancing medicine through scientific innovation in 2016. Our researchers were actively investigating the causes of potential treatments for a wide-range of diseases in our four areas of focus: Acute Care/Trauma, Addiction, Infectious Disease (HIV/AIDS) and Health Services. Here are just some of the highlights in research at MMRF from the past year.



Posted on November 18, 2016
BRINK study finds patients with moderate chronic kidney disease (CKD) have increased risk for dementia
Approximately 3 million patients live with this level of CKD in the United States

brainimagePatients with moderate chronic kidney disease (CKD), who have lost more than half of their kidney function score worse on tests of memory and decision-making skills than those without CKD, according to the BRain IN Kidney disease (BRINK) study.

Approximately 3 million people live with moderate CKD in the United States, more often affecting the elderly. In patients with CKD their kidneys are no longer functioning at full capacity, but they don’t yet need dialysis.

“What I and others have found is that as kidney function declines, so does brain function,” Dr. Anne Murray, Principal Investigator of the BRINK study said. Patients with CKD have a 50-60 percent increased risk of dementia. (Read the full story about the BRINK study)

New policy on the dissemination of NIH-funded clinical trial information goes into effect January 18, 2017

image of the new NIH policy logoEarly next year, the National Institutes of Health (NIH) will expand its registration requirement to all clinical trials funded in whole or in part by the NIH. NIH funded Principal Investigators will now be expected to ensure that all trials are registered at, and that the studies’ summary results information is submitted to site in a timely manner.

Click here to read more about the NIH Expanded Policy. . . . is changing the way applicants apply for grants

logo for grants dot gov is updating its process to make it easier for applicants to apply for federal grants. In December 2017, will phase out the Legacy Application Package, and applicants will instead apply through Workspace.

Read the full story about application changes on . . .


Watch the video to learn about our history