Improving patient care and the health of our community through research and education.

MMRF Logo for Website

The Minneapolis Medical Research Foundation (MMRF) is a subsidiary of Hennepin Healthcare System, Inc., and operates as the research arm of Hennepin County Medical Center, an acute care research and teaching hospital in Minneapolis. MMRF is one of the largest nonprofit medical research organizations in Minnesota and consistently ranks in the top ten percent of all institutions receiving research funding from the National Institutes of Health (NIH).


Learn more about our Research Programs 

Read Our MMRF Brochure


 New Name, Same Mission

Since 1952, the mission of the Minneapolis Medical Research Institute (MMRF) has been improving patient care and the health of our community through research and education. With a current focus on four areas – Acute Care/Trauma, Addiction, Health Services and Infectious Disease (HIV/AIDS) – we support and oversee the medical research conducted at HCMC, the flagship hospital of the Hennepin Healthcare system. Later this year, the MMRF name and logo will change to better align with our parent and affiliate organizations. While our mission will stay the same, MMRF will re-brand as the Hennepin Healthcare Research Institute. Read more about the name change and research’s role in the Hennepin Healthcare system.


Posted May 22, 2018
Study finds integrated medical care and social support services affects health care use among Medicaid expansion enrollees

Graphic of Integrated Care


Two studies published this month in Medical Care Research & Review found that providing integrated medical care and social support services led to increased use of primary care among very low-income adults in Hennepin County who were enrolled in a Medicaid accountable care organization (ACO) between 2012 and 2014. Strong primary care relationships, combined with mental health treatment, were linked to improved quality of life among enrollees of the ACO. Hennepin Healthcare’s Kate Vickery, MD, MSc, along with researchers from the University of Minnesota School of Public Health and Clinical and Translational Science Institute, Hennepin County and the University of Michigan conducted the study. Read more…

MMRF investigators awarded ClearWay Minnesota grant to provide smoking cessation to people leaving the Hennepin County Jail

While smoking rates are dropping in the general population, they’re not for people involved in the justice system. Tyler Winkelman, MD, MSc, along with co-investigator Andrew (Drew) Busch, PhD, LP, are starting a new two-year medical research study to provide smoking cessation to people leaving the Hennepin County Jail. Smoking is not allowed in jail. Intervention at this critical time may help people continue to abstain from smoking after they leave jail. The trial, which is funded by a grant from ClearWay Minnesota, is a first of its kind in the country. Read more about Dr. Winkelman’s and Dr. Busch’s research on

MMRF investigator responds to Minneapolis’ proposal to raise the age to buy tobacco

MMRF investigator and Chief of Clinical Pharmacology and Toxicology at HCMC Paul Pentel, MD, was recently interviewed by Minnesota Public Radio about the City of Minneapolis’ proposal to raise the age to buy tobacco from 18 to 21. Minneapolis would be following suit after several other Minnesota municipalities have made it illegal to sell tobacco to anyone under the age of 21. “With Minneapolis joining surrounding communities in enacting T-21, this is expected to prevent 30,000 adolescents from becoming smokers over the next 15 years,” said Dr. Pentel. “That’s a huge impact for a very simple intervention.” Read more…

Posted May 8, 2018
SRTR establishes living donor registry to study the long-term outcomes of living donation


The Scientific Registry of Transplant Recipients (SRTR) recently launched a pilot project called the Living Donor Collective (LDC) to study the long-term effects of donating one’s kidney or liver. This living donor registry, which began enrolling patients in 2018, is starting at 16 transplant programs (10 kidney and 6 liver) across the United States. Additional centers will be added when the pilot phase is completed by the end of 2020. Read more. . .

Watch the Video to Learn About Our History